In recent years, federal and state policy makers have expressed concern about retail pharmacy closures throughout the US. However, there is a dearth of timely information on the extent of such closures. We linked data from the National Council for Prescription Drug Programs on all US retail pharmacies to county-level data from the National Center for Health Statistics and ZIP Code Tabulation Area data from the American Community Survey to determine the number and percentage of pharmacy closures during the period 2010–21; identify pharmacy, neighborhood, and market characteristics...
In recent years, federal and state policy makers have expressed concern about retail pharmacy closures throughout the US. However, there is a dearth of timely information on the extent of such closures. CHAMP faculty member Jenny Guadamuz and coauthors linked data from the National Council for Prescription Drug Programs on all US retail pharmacies to county-level data from the National Center for Health Statistics and ZIP Code Tabulation Area data from the American Community Survey to determine the number and percentage of pharmacy closures during the period 2010–21; identify...
Minoritized racial and ethnic populations, including American Indian and Alaska Native, Asian and Pacific Islander, Black, and Hispanic communities, endure complex and persistent inequities in breast cancer outcomes. Socioeconomic factors, limited health care access, cultural and linguistic barriers, along with environmental factors, all contribute to disparities in breast cancer prevention, screening, treatment, and survivorship. Although disparities in breast cancer treatment have been well documented,...
Certain populations have been historically underrepresented in clinical trials. Broadening eligibility criteria is one approach to inclusive clinical research and achieving enrollment goals. How broadened trial eligibility criteria affect the diversity of eligible participants is unknown.
Methods
Using a nationwide electronic health record–derived deidentified database, we identified a retrospective cohort of patients diagnosed with 22 cancer types between April 1, 2013 and December 31, 2022 who received systemic therapy (N=...
ImportanceThere is increasing recognition from regulatory agencies that racial and ethnic representation in clinical trials is inadequate and linked to health inequities. The extent of racial inequities in clinical trial participation is unclear because prior studies have synthesized enrollment data from published trials, which often do not report participant race and ethnicity.
ObjectiveTo evaluate racial and ethnic inequities in oncology clinical trial participation in a contemporary cohort of patients with cancer before and...
While breast cancer studies often aggregate Asian/Pacific Islander (API) women, as a single group or exclude them, this population is heterogeneous in terms of genetic background, environmental exposures, and health-related behaviors, potentially resulting in different cancer outcomes. Our purpose was to evaluate risks of contralateral breast cancer (CBC) among subgroups of API women with breast cancer.
Methods
We conducted a retrospective cohort study of women ages 18 + years diagnosed with stage I–III breast cancer between...
Although telemedicine was seen as a way to improve cancer care during the coronavirus disease (COVID-19) pandemic, there is limited information regarding inequities in its uptake. This study assessed sociodemographic factors associated with telemedicine use among patients initiating treatment for 20 common cancers.
Methods
This retrospective cohort study used deidentified electronic health record–derived patient data from a nationwide network of community cancer practices, linked to area-level Census information. We included...
Lower neighborhood socioeconomic status (SES) is associated with suboptimal cancer care and reduced survival. Most studies examining cancer inequities across area-level socioeconomic status tend to use less granular or unidimensional measures and pre-date the COVID-19 pandemic. Here, we examined the association of area-level socioeconomic status on real-world treatment initiation and overall survival among adults with 20 common cancers.
Methods
This retrospective cohort study used electronic health record–derived deidentified data (...
Biologics are the fastest growing medication class in the US and account for an increasing portion of health care costs. In the US, the Biologics Price Competition and Innovation Act of 2009 created an abbreviated approval pathway to expand access to safe and effective biological products.1 Pivot et al2 report the...
This study quantifies the prevalence and trends in weekly PrEP coverage at the national, state and county-level, before and during the COVID-19 pandemic in the United States.We estimated weekly PrEP coverage using longitudinal individual-level pharmacy claims from IQVIA LRx for a cohort of PrEP users (N = 287,493) ages 16 to 85 years between December 29th, 2019 and November 8th, 2020. Weekly PrEP coverage was defined as PrEP use among individuals at high risk for HIV. We conducted an interrupted time series analysis to quantify changes in weekly PrEP coverage before (December 29th,...
